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Republic of Korea - Final Regulatory Action
4-Aminobiphenyl CAS number:
92-67-1
Date circular:
12/12/2004

Chemical name: [1,1'-Biphenyl]-4-amine

Final regulatory action has been taken for the category: Industrial

Final regulatory action: The chemical is Banned

Use or uses prohibited by the final regulatory action:

4-aminobiphenyl, its hydrochloride and mixtures containing 0.1% or more of any of these chemicals are banned for manufacture, import and use as an industrial chemical. No remaining uses are allowed, except for the use mentioned below.

Use or uses that remain allowed:

Use of the chemicals for research or laboratory purposes is allowed.

The final regulatory action was based on a risk or hazard evaluation: Yes

Summary of the final regulatory action:

4-aminobiphenyl, its hydrochloride and mixtures containing 1% or more of any of these chemicals are banned for manufacture, import and use as an industrial chemical. No remaining uses are allowed.

The reasons for the final regulatory action were relevant to: Human health

Summary of known hazards and risks to human health:

4-aminobiphenyl is a carcinogen to humans (IARC group 1). It can cause dyspnea and CNS depression. In experimental animals, it has produced bladder and liver tumours. 4-Aminobiphenyl appears to be one of the most potent of the known bladder carcinogens

Expected effect of the final regulatory action in relation to human health:

It is expected that the regulatory action will significantly reduce the potential risk of carcinogenic effect to workers and others involved in dye manufacturing industry..

Date of entry into force of the final regulatory action: 13/11/2003

4-Aminobiphenyl wree banned for manufacture, use and import by MOE's Public Notice No. 1991-44(9 Aug.1991). The notice was amended several times and its hydrochloride were also involved in banned chemicals on 1 June 1996. The final amended notice took into force on 13 November 2003.